At a ten-year college reunion, five former roommates gather in their old dorm for a night of champagne swilling. Their lives have all taken different directions with varying degrees of success on the personal and professional front. One is trophy wife with two kids. One is an investment banker with no time for a personal life. One is a doctor, married with two kids with no time for herself. One is an academic still living like a college student. And the last is a socialite, still jet-setting around with no career or roots.

The bonds are still tight at the reunion and the women decide to open up about their lives, each revealing a secret. The married woman is having an affair. The investment banker did some insider trading. The doctor writes prescriptions for pills on the other side. The academic plagiarized. And the socialite had to go to rehab. They all hug and go home. A week later, each receives a blackmail note. It's clearly an inside job and as two set out to investigate the cause of the betrayal...